السلام عليكم
دومبيريدون
Some commonly used brand names are
In Canada
[Motilium[reg
Not commercially available in the U.S
Category
Anti-emetic
Dopaminergic blocking agent
Description
Domperidone(dom-PER-i-done) is a medicine that increases the movements or contractions of the stomach and bowel
Domperidone is also used to treat nausea and vomiting caused by other drugs used to treat Parkinson's Disease
Domperidone is to be given only by or under the immediate supervision of your doctor
It is available in the following dosage forms
Oral
Tablets
وكذلك يوجد منه شرابsyrup
Before Receiving This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do
This is a decision you and your doctor will make. For domperidone the following should be considered
Allergies-Tell your doctor if you have ever had any unusual or allergic reaction to domperidone
Pregnancy-domperidone has not been studied in pregnant women. However, domperidone has not been shown to cause birth defects or other problems in animal studies
Breast-feeding- Domperidone passes into the breast milk, but it is not known if domperidone will cause unwanted effects in the newborn. It may be necessary for you to take another medicine or to stop breast-feeding during treatment. Be sure you have discussed the risks and benefits of the medicine with your doctor
Children-Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of domperidone in children with use in other age groups
Older adults-Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing the use of domperidone in the elderly with use in other age groups
Other medicines-Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary
Tell your doctor or pharmacist if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine, especially
Monoamine oxidase (MAO) inhibitors
(furazolidone [e.g., Furoxone]
phenelzine [e.g., Nardil]
procarbazine [e.g., Matulane]
selegilene [e.g., Eldepryl]
tranylcypromine [e.g., Parnate]
Other medical problems-The presence of other medical problems may affect the use of domperidone. Make sure you tell your doctor if you have any other medical problems, especially
Bleeding from the stomach or other problems involving the bowels
Pituitary (brain) tumor
Liver disease
Medicine sensitivity to domperidone
Proper Use of This Medicine
Dosing-The dose of domperidone will be different for different patients. Follow your doctor's orders or the directions on the label
The following information includes only the average doses of domperidone.If your dose is different, do not change it unless your doctor tells you to do so
The number of tablets of that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem
for which you are taking domperidone
For oral dosage form
Treatment of gastrointestinal motility disorders
Adults-10 milligrams (mg) three to four times daily. Some patients may require higher doses up to 20 mg three or four times daily
Nausea and vomiting
Adults-20 milligrams (mg) three to four times daily
Missed dose-If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses
Storage-To store this medicine
Keep out of the reach of children
Store away from heat and direct light
Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down
Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children
Precautions While Receiving This Medicine
It is very important that your doctor check your progress at regular visits . This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it
If your symptoms do not improve within a few days or if they become worse, check with your doctor
Side Effects of This Medicine
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention
Symptoms of overdose
Get emergency help immediately if any of the following symptoms of overdose occur
Check with your doctor immediately if any of the following side effects occur
Less common
Loss of balance or muscle control; swelling of the mouth
Rare
Fast, irregular, pounding, or racing heartbeat or pulse; swelling of face, hands, lower legs, or feet
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome
Less common
Breast milk flowing from the nipple; dry mouth; swelling of the breast in the male; headache; hives; hot flashes; itching of skin; itching, redness, pain, or swelling of eye; menstrual irregularities; pain in the breast
Rare
Change in need to urinate; change in appetite; constipation; diarrhea; burning, difficult, or painful urination ; difficulty in speaking ; dizziness; drowsiness; heartburn; irritability; lack or loss of strength; leg cramps; mental dullness; nervousness; palpitations; sluggishness; stomach cramps; thirst; tiredness; weakness